The average train between Cuenca and Santander takes 6h 39m and the fastest train takes 5h 16m. The train service runs several times per day from Cuenca to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Cuenca and Santander. The earliest departure is at 7:07 AM in the morning, and the last departure from Cuenca is at 10:34 PM which arrives into Santander at 12:05 PM. All services require a transfer, and take on average 6h 39m. The schedules shown below are for the next available departures.

5h 43m • 1 change

5h 49m • 1 change

5h 16m • 1 change

5h 44m • 1 change

5h 43m • 1 change

5h 49m • 1 change

5h 16m • 1 change

5h 44m • 1 change

5h 56m • 1 change

5h 49m • 1 change

5h 16m • 1 change

5h 44m • 1 change

5h 44m • 1 change

5h 42m • 1 change

5h 40m • 1 change
Arrives next day

13h 31m • 1 change

5h 43m • 1 change

5h 49m • 1 change

5h 16m • 1 change

5h 44m • 1 change

5h 43m • 1 change

5h 49m • 1 change

5h 16m • 1 change

5h 44m • 1 change
Want to know about travelling from Cuenca to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Cuenca to Santander. However, there are services departing from Cuenca station and arriving at Santander station via Madrid Chamartín. The journey, including transfers, takes approximately 6h 39m.
Cuenca to Santander train services, operated by Renfe Viajeros, depart from Cuenca Fernando Zobel station.
Cuenca to Santander train services, operated by Renfe Viajeros, arrive at Santander station.
Book your Cuenca to Santander train tickets online with Renfe Viajeros, Renfe AVE and 2 other operators.
The distance between Cuenca and Santander is 402.4 km. The road distance is 636 km.
You can take a train from Cuenca Fernando Zobel to Santander via Madrid Chamartín in around 6h 26m.