The average train between Crewe and Southampton takes 3h 58m and the fastest train takes 3h 16m. There is a train service every few hours from Crewe to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Crewe and Southampton. The earliest departure is at 5:37 AM in the morning, and the last departure from Crewe is at 10:04 PM which arrives into Southampton at 7:57 AM. All services require a transfer at London Euston and take an average of 3h 58m. The schedules shown below are for the next available departures.


3h 26m • 2 changes


3h 26m • 2 changes


3h 26m • 2 changes


3h 23m • 2 changes


3h 44m • 2 changes


3h 18m • 2 changes


3h 16m • 2 changes


3h 26m • 2 changes


3h 44m • 2 changes


3h 18m • 2 changes


3h 16m • 2 changes


3h 26m • 2 changes
Want to know about travelling from Crewe to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Crewe to Southampton. However, there are services departing from Crewe station and arriving at Southampton station via London Euston. The journey, including transfers, takes approximately 3h 58m.
Crewe to Southampton train services, operated by Avanti West Coast, depart from Crewe station.
Crewe to Southampton train services, operated by Avanti West Coast, arrive at Southampton Central station.
Book your Crewe to Southampton train tickets online with Avanti West Coast, London Underground (Tube) and South Western Railway.
The distance between Crewe and Southampton is 254.1 km. The road distance is 383 km.
You can take a train from Crewe to Southampton Central via London Euston, Euston station, Waterloo Station, and London Waterloo in around 3h 22m.