The average train between Crewe and Brussels takes 4h 57m and the fastest train takes 4h 2m. The train service runs several times per day from Crewe to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Crewe and Brussels. The earliest departure is at 6:55 AM in the morning, and the last departure from Crewe is at 10:04 PM which arrives into Brussels at 10:05 AM. All services require a transfer at London Euston and take an average of 4h 57m. The schedules shown below are for the next available departures.

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Want to know about travelling from Crewe to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Crewe to Brussels. However, there are services departing from Crewe station and arriving at Brussels station via London Euston. The journey, including transfers, takes approximately 4h 57m.
Crewe to Brussels train services, operated by Avanti West Coast, depart from Crewe station.
Crewe to Brussels train services, operated by Avanti West Coast, arrive at Brussel-Zuid / Bruxelles-Midi station.
Book your Crewe to Brussels train tickets online with Avanti West Coast and Eurostar.
The distance between Crewe and Brussels is 527.7 km. The road distance is 624 km.
You can take a train from Crewe to Brussel-Zuid / Bruxelles-Midi via London Euston and London St Pancras Intl in around 4h 49m.