The average train between Chicago and O'Fallon Junction takes 6h 35m and the fastest train takes 5h 25m. The train service runs several times per day from Chicago to O'Fallon Junction. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Chicago and O'Fallon Junction. The earliest departure is at 7:15 AM in the morning, and the last departure from Chicago is at 7:10 PM which arrives into O'Fallon Junction at 6:00 AM. All services require a transfer at St. Louis and take an average of 6h 35m. The schedules shown below are for the next available departures.

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Want to know about travelling from Chicago to O'Fallon Junction? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Chicago to O'Fallon Junction. However, there are services departing from Chicago station and arriving at O'Fallon Junction station via St. Louis. The journey, including transfers, takes approximately 6h 35m.
Chicago to O'Fallon Junction train services, operated by Amtrak, depart from Chicago Union Station.
Chicago to O'Fallon Junction train services, operated by Amtrak, arrive at St. Louis station.
The distance between Chicago and O'Fallon Junction is 422.5 km. The road distance is 479 km.
Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $75–180 and the journey takes 4h 46m.