Yes, there is a direct train departing from Chicago Union Station station and arriving at Buffalo Depew Station station. Services depart twice daily, and operate every day. The journey takes approximately 10h 16m.More details
The distance between Chicago and Buffalo Depew Station is 462 miles. The road distance is 538.5 miles.Get driving directions
Chicago to Buffalo Depew Station train services, operated by Amtrak, depart from Chicago Union Station.More details
Chicago to Buffalo Depew Station train services, operated by Amtrak, arrive at Buffalo Depew Station.More details
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Buffalo Depew Station is 1h ahead of Chicago. It is currently 12:42 PM in Chicago and 1:42 PM in Buffalo Depew Station.
There are 158+ hotels available in Buffalo Depew Station. Prices start at $100 USD per night.More details
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