The average train between Cheltenham and Slough takes 2h and the fastest train takes 1h 48m. There is a train service every few hours from Cheltenham to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Cheltenham and Slough. The earliest departure is at 5:53 AM in the morning, and the last departure from Cheltenham is at 9:05 PM which arrives into Slough at 11:19 PM. All services require a transfer, and take on average 2h. The schedules shown below are for the next available departures.

1h 58m • 1 change

1h 59m • 1 change

1h 58m • 1 change

1h 57m • 1 change

2h 14m • 1 change

2h 20m • 1 change

2h 5m • 1 change

1h 54m • 1 change

2h 12m • 1 change

2h 5m • 1 change

1h 58m • 1 change

1h 58m • 1 change

2h 14m • 1 change

2h 20m • 1 change

2h 5m • 1 change

1h 54m • 1 change
Want to know about travelling from Cheltenham to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Cheltenham to Slough. However, there are services departing from Cheltenham station and arriving at Slough station via Reading. The journey, including transfers, takes approximately 2h.
Cheltenham to Slough train services, operated by Great Western Railway (GWR), depart from Cheltenham Spa station.
Cheltenham to Slough train services, operated by Great Western Railway (GWR), arrive at Reading station.
Book your Cheltenham to Slough train tickets online with Great Western Railway (GWR) and Elizabeth Line (TfL).
The distance between Cheltenham and Slough is 111.1 km. The road distance is 164 km.
Great Western Railway (GWR) operates a train from Cheltenham Spa to Reading hourly. Tickets cost £35–70 and the journey takes 1h 31m.