The average train between Cheltenham Spa and Slough takes 2h 1m and the fastest train takes 1h 48m. There is a train service every few hours from Cheltenham Spa to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Cheltenham Spa and Slough. The earliest departure is at 5:53 AM in the morning, and the last departure from Cheltenham Spa is at 9:02 PM which arrives into Slough at 10:58 PM. All services require a transfer, and take on average 2h 1m. The schedules shown below are for the next available departures.

2h 14m • 1 change

2h 20m • 1 change

2h 5m • 1 change

1h 54m • 1 change

2h 14m • 1 change

2h 20m • 1 change

2h 5m • 1 change

1h 54m • 1 change

2h 14m • 1 change

2h 20m • 1 change

2h 5m • 1 change

1h 54m • 1 change
Want to know about travelling from Cheltenham Spa to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Cheltenham Spa to Slough. However, there are services departing from Cheltenham Spa station and arriving at Slough station via Reading. The journey, including transfers, takes approximately 2h 1m.
Cheltenham Spa to Slough train services, operated by Great Western Railway (GWR), depart from Cheltenham Spa station.
Cheltenham Spa to Slough train services, operated by Great Western Railway (GWR), arrive at Reading station.
Book your Cheltenham Spa to Slough train tickets online with Great Western Railway (GWR) and Elizabeth Line (TfL).
The distance between Cheltenham Spa and Slough is 112.3 km. The road distance is 164 km.
Great Western Railway (GWR) operates a train from Cheltenham Spa to Reading hourly. Tickets cost £35–70 and the journey takes 1h 31m.