The average train between Carluke and Manchester takes 4h 14m and the fastest train takes 3h 16m. There is a train service every few hours from Carluke to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Carluke and Manchester. The earliest departure is at 12:08 AM at night, and the last departure from Carluke is at 11:47 PM which arrives into Manchester at 8:53 AM. All services require a transfer at Motherwell and take an average of 4h 14m. The schedules shown below are for the next available departures.


12h 39m • 2 changes


3h 20m • 2 changes


3h 19m • 2 changes


3h 16m • 2 changes


3h 55m • 2 changes


3h 22m • 2 changes


3h 21m • 2 changes


3h 44m • 2 changes


8h 45m • 2 changes


3h 55m • 2 changes


3h 22m • 2 changes


3h 21m • 2 changes


8h 45m • 2 changes


3h 55m • 2 changes


3h 22m • 2 changes


3h 21m • 2 changes
Want to know about travelling from Carluke to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Carluke to Manchester. However, there are services departing from Carluke station and arriving at Manchester station via Lancaster. The journey, including transfers, takes approximately 4h 14m.
Carluke to Manchester train services, operated by ScotRail, depart from Motherwell station.
Carluke to Manchester train services, operated by ScotRail, arrive at Manchester Oxford Road station.
Book your Carluke to Manchester train tickets online with ScotRail, TransPennine Express and 2 other operators.
The distance between Carluke and Manchester is 270.9 km. The road distance is 348 km.
You can take a train from Carluke to Manchester Oxford Road via Motherwell and Lancaster in around 3h 58m.