The average train between Carlisle and Middlesex takes 4h 36m and the fastest train takes 3h 56m. There is a train service every few hours from Carlisle to Middlesex. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Carlisle and Middlesex. The earliest departure is at 1:45 AM at night, and the last departure from Carlisle is at 8:08 PM which arrives into Middlesex at 5:54 AM. All services require a transfer, and take on average 4h 36m. The schedules shown below are for the next available departures.

5h 19m • 1 change

4h 2m • 1 change

3h 58m • 1 change

4h 14m • 1 change

5h 46m • 1 change

5h 19m • 1 change

4h 2m • 1 change

3h 58m • 1 change

5h 46m • 1 change

5h 19m • 1 change

4h 2m • 1 change

3h 58m • 1 change
Want to know about travelling from Carlisle to Middlesex? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Carlisle to Middlesex. However, there are services departing from Carlisle station and arriving at Middlesex station via London Euston. The journey, including transfers, takes approximately 4h 36m.
Carlisle to Middlesex train services, operated by Caledonian Sleeper, depart from Carlisle station.
Carlisle to Middlesex train services, operated by Caledonian Sleeper, arrive at London Euston station.
Book your Carlisle to Middlesex train tickets online with Caledonian Sleeper, London Overground and Avanti West Coast.
The distance between Carlisle and Middlesex is 414 km. The road distance is 488 km.
Avanti West Coast operates a train from Carlisle to London Euston hourly. Tickets cost £100–180 and the journey takes 3h 26m. Caledonian Sleeper also services this route twice daily.