The average train between Buffalo and Philadelphia takes 10h 45m and the fastest train takes 9h 44m. The train service runs several times per day from Buffalo to Philadelphia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Buffalo and Philadelphia. The earliest departure is at 4:28 AM at night, and the last departure from Buffalo is at 12:25 PM which arrives into Philadelphia at 12:51 AM. All services require a transfer, and take on average 10h 45m. The schedules shown below are for the next available departures.

9h 44m • 1 change

10h 1m • 1 change
Arrives next day

12h 26m • 1 change

9h 44m • 1 change

10h 1m • 1 change
Arrives next day

12h 26m • 1 change

9h 50m • 1 change

10h 10m • 1 change
Arrives next day

12h 26m • 1 change

9h 50m • 1 change

10h 8m • 1 change
Arrives next day

12h 26m • 1 change
Want to know about travelling from Buffalo to Philadelphia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Buffalo to Philadelphia. However, there are services departing from Buffalo station and arriving at Philadelphia station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 10h 45m.
Buffalo to Philadelphia train services, operated by Amtrak, depart from Buffalo station.
Buffalo to Philadelphia train services, operated by Amtrak, arrive at 30th Street Station.
Book your Buffalo to Philadelphia train tickets online with Amtrak, Amtrak Northeast Regional and Amtrak Acela.
The distance between Buffalo and Philadelphia is 449.8 km. The road distance is 850 km.
You can take a train from Buffalo to 30th Street Station via Ny Moynihan Train Hall At Penn Station in around 10h 14m.