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Buffalo to Mystic trains

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Trip Overview

The average train between Buffalo and Mystic takes 15h and the fastest train takes 11h 19m. The train service runs several times per day from Buffalo to Mystic. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h
Duration
573 mi
Distance
$376
Average price
3 times a day
Frequency

Buffalo to Mystic train times

Trains run 3 times a day between Buffalo and Mystic. The earliest departure is at 4:28 AM at night, and the last departure from Buffalo is at 12:25 PM which arrives into Mystic at 8:27 AM. All services require a transfer, and take on average 15h. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak20h 2m • 1 change

Departing Friday, November 6, 2026

  •  → 

    AmtrakAmtrak12h 48m • 1 change
  •  → 

    AmtrakAmtrak12h 40m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak20h 2m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    AmtrakAmtrak11h 19m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak20h 2m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    AmtrakAmtrak11h 19m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak20h 2m • 1 change

Departing Monday, November 9, 2026

  •  → 

    AmtrakAmtrak12h 48m • 1 change
  •  → 

    AmtrakAmtrak12h 40m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak20h 2m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    AmtrakAmtrak12h 48m • 1 change
  •  → 

    AmtrakAmtrak12h 40m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak20h 2m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    AmtrakAmtrak12h 48m • 1 change
  •  → 

    AmtrakAmtrak12h 40m • 1 change

Frequently asked questions

Want to know about travelling from Buffalo to Mystic? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Mystic.ExpandLaunch map view
  • Distance: 573.3 mi
  • Duration: 15h

What companies run services between Buffalo, NY, USA and Mystic, CT, USA?

You can take a train from Buffalo to Mystic Station via Ny Moynihan Train Hall At Penn Station in around 12h.

Operators