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Buffalo to Milwaukee trains

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Trip Overview

The average train between Buffalo and Milwaukee takes 25h 35m and the fastest train takes 25h 17m. The train runs, on average, 6 times per week from Buffalo to Milwaukee. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 35m
Duration
619 mi
Distance
$428
Average price
6 times a week
Frequency

Buffalo to Milwaukee train times

Trains run 6 times a week between Buffalo and Milwaukee. The earliest departure is at 12:15 PM in the afternoon, and the last departure from Buffalo is at 12:25 PM which arrives into Milwaukee at 12:42 PM. All services require a transfer at Buffalo Depew Station and take an average of 25h 35m. The schedules shown below are for the next available departures.

Departing Wednesday, October 28, 2026

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    Arrives next day

    VIA RailAmtrakAmtrak25h 27m • 2 changes

Departing Thursday, October 29, 2026

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    Arrives next day

    VIA RailAmtrakAmtrak25h 27m • 2 changes

Departing Friday, October 30, 2026

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    Arrives next day

    VIA RailAmtrakAmtrak25h 27m • 2 changes

Departing Saturday, October 31, 2026

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    Arrives next day

    VIA RailAmtrakAmtrak26h 27m • 2 changes

Departing Sunday, November 1, 2026

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    Arrives next day

    VIA RailAmtrakAmtrak25h 27m • 2 changes

Departing Monday, November 2, 2026

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    Arrives next day

    AmtrakAmtrakAmtrak25h 17m • 2 changes

Frequently asked questions

Want to know about travelling from Buffalo to Milwaukee? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Milwaukee.ExpandLaunch map view
  • Distance: 618.6 mi
  • Duration: 25h 35m

What companies run services between Buffalo, NY, USA and Milwaukee, WI, USA?

You can take a train from Buffalo to Milwaukee via Buffalo Depew Station and Chicago Union Station in around 14h 19m.

Operators