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Buffalo to Framingham trains

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Trip Overview

The train between Buffalo and Framingham takes 12h 36m. There is at least one train per day from Buffalo to Framingham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 36m
Duration
475 mi
Distance
$333
Average price
Once daily
Frequency

Buffalo to Framingham train times

Trains run once daily between Buffalo and Framingham. The service departs Buffalo at 7:22 AM in the morning, which arrives into Framingham at 19:58:00. All services require a transfer, and take on average 12h 36m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    AmtrakAmtrak12h 36m • 1 change

Departing Monday, November 9, 2026

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    AmtrakAmtrak12h 36m • 1 change

Departing Tuesday, November 10, 2026

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    AmtrakAmtrak12h 36m • 1 change

Departing Wednesday, November 11, 2026

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    AmtrakAmtrak12h 36m • 1 change

Departing Thursday, November 12, 2026

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    AmtrakAmtrak12h 36m • 1 change

Departing Friday, November 13, 2026

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    AmtrakAmtrak12h 36m • 1 change

Departing Saturday, November 14, 2026

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    AmtrakAmtrak12h 36m • 1 change

Frequently asked questions

Want to know about travelling from Buffalo to Framingham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Framingham.ExpandLaunch map view
  • Distance: 474.9 mi
  • Duration: 12h 36m

What companies run services between Buffalo, NY, USA and Framingham, MA, USA?

Amtrak operates a train from Buffalo Depew Station to Framingham Amtrak once daily. Tickets cost $250–400 and the journey takes 10h 53m.

Operators