The average train between Buffalo and Baltimore takes 13h 14m and the fastest train takes 10h 51m. The train service runs several times per day from Buffalo to Baltimore. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Buffalo and Baltimore. The earliest departure is at 4:28 AM at night, and the last departure from Buffalo is at 12:25 PM which arrives into Baltimore at 6:02 AM. All services require a transfer, and take on average 13h 14m. The schedules shown below are for the next available departures.

10h 51m • 1 change

11h 19m • 1 change
Arrives next day

17h 37m • 1 change

10h 51m • 1 change

11h 19m • 1 change
Arrives next day

17h 37m • 1 change

10h 51m • 1 change

11h 19m • 1 change
Arrives next day

17h 37m • 1 change

10h 51m • 1 change

11h 19m • 1 change
Arrives next day

17h 11m • 1 change
Want to know about travelling from Buffalo to Baltimore? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Buffalo to Baltimore. However, there are services departing from Buffalo station and arriving at Baltimore station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 13h 14m.
Buffalo to Baltimore train services, operated by Amtrak, depart from Buffalo station.
Buffalo to Baltimore train services, operated by Amtrak, arrive at Baltimore Penn Station.
Book your Buffalo to Baltimore train tickets online with Amtrak, Amtrak Acela and Amtrak Northeast Regional.
The distance between Buffalo and Baltimore is 442.6 km. The road distance is 1,002 km.
You can take a train from Buffalo to Baltimore Penn Station via Ny Moynihan Train Hall At Penn Station in around 11h 34m.