The average train between Brussels and Issoire takes 10h 37m and the fastest train takes 7h 21m. The train service runs several times per day from Brussels to Issoire. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Brussels and Issoire. The earliest departure is at 6:27 AM in the morning, and the last departure from Brussels is at 6:09 PM which arrives into Issoire at 10:16 AM. All services require a transfer at Lyon Part Dieu and take an average of 10h 37m. The schedules shown below are for the next available departures.


8h 41m • 2 changes

7h 38m • 2 changes

7h 21m • 2 changesArrives next day


13h 31m • 2 changes

8h 41m • 2 changes

7h 38m • 2 changes

7h 21m • 2 changesArrives next day


13h 31m • 2 changes

8h 41m • 2 changes

7h 38m • 2 changes

7h 21m • 2 changesArrives next day


13h 31m • 2 changes

8h 41m • 2 changes

7h 38m • 2 changes

7h 21m • 2 changesArrives next day


13h 31m • 2 changes

8h 41m • 2 changes

7h 38m • 2 changes

7h 21m • 2 changesArrives next day


15h 45m • 2 changesWant to know about travelling from Brussels to Issoire? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brussels to Issoire. However, there are services departing from Brussel-Zuid / Bruxelles-Midi station and arriving at Clermont Ferrand station via Lyon Part Dieu station. The journey, including transfers, takes approximately 10h 37m.
Brussels to Issoire train services, operated by TGV inOui, depart from Brussel-Zuid / Bruxelles-Midi station.
Brussels to Issoire train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Clermont Ferrand station.
Book your Brussels to Issoire train tickets online with Omio.
The distance between Brussels and Issoire is 595.6 km. The road distance is 723 km.
You can take a train from Brussel-Zuid / Bruxelles-Midi to Issoire via Lyon Part Dieu and Clermont Ferrand in around 8h 4m.