The average train between Brookline and Baltimore takes 7h 24m and the fastest train takes 6h 11m. There is a train service every few hours from Brookline to Baltimore. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Brookline and Baltimore. The earliest departure is at 5:05 AM in the morning, and the last departure from Brookline is at 7:52 PM which arrives into Baltimore at 7:38 AM. All services require a transfer, and take on average 7h 24m. The schedules shown below are for the next available departures.

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Want to know about travelling from Brookline to Baltimore? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brookline to Baltimore. However, there are services departing from Brookline station and arriving at Baltimore station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 7h 24m.
Brookline to Baltimore train services, operated by Amtrak Acela, depart from Boston station.
Brookline to Baltimore train services, operated by Amtrak Acela, arrive at Baltimore Penn Station.
Book your Brookline to Baltimore train tickets online with Amtrak Acela and Amtrak.
The distance between Brookline and Baltimore is 572.4 km. The road distance is 667 km.
You can take a train from Boston to Baltimore Penn Station via Ny Moynihan Train Hall At Penn Station in around 6h 37m.