The average train between Baltimore and Brookline takes 7h 15m and the fastest train takes 6h 11m. There is a train service every few hours from Baltimore to Brookline. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Baltimore and Brookline. The earliest departure is at 5:22 AM in the morning, and the last departure from Baltimore is at 10:51 PM which arrives into Brookline at 9:25 AM. All services require a transfer, and take on average 7h 15m. The schedules shown below are for the next available departures.

7h 27m • 1 change

6h 25m • 1 change

6h 43m • 1 change

7h 3m • 1 change

6h 11m • 1 change

7h 20m • 1 change

7h 29m • 1 change

7h 17m • 1 change

6h 11m • 1 change

7h 20m • 1 change

7h 29m • 1 change

7h 17m • 1 change

6h 11m • 1 change

7h 20m • 1 change

7h 29m • 1 change

7h 17m • 1 change
Want to know about travelling from Baltimore to Brookline? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Baltimore to Brookline. However, there are services departing from Baltimore station and arriving at Brookline station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 7h 15m.
Baltimore to Brookline train services, operated by Amtrak, depart from Baltimore Penn Station.
Baltimore to Brookline train services, operated by Amtrak, arrive at Boston station.
Book your Baltimore to Brookline train tickets online with Amtrak and Amtrak Acela.
The distance between Baltimore and Brookline is 572.4 km. The road distance is 667 km.
You can take a train from Baltimore Penn Station to Boston via Ny Moynihan Train Hall At Penn Station in around 6h 45m.