The average train between Ayr and Middlesbrough takes 5h 54m and the fastest train takes 4h 45m. There is a train service every few hours from Ayr to Middlesbrough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Ayr and Middlesbrough. The earliest departure is at 5:36 AM in the morning, and the last departure from Ayr is at 10:05 PM which arrives into Middlesbrough at 8:30 AM. All services require a transfer at Glasgow Central and take an average of 5h 54m. The schedules shown below are for the next available departures.



5h 2m • 3 changes



5h 33m • 3 changes



5h 33m • 3 changes



5h 33m • 3 changes



5h 13m • 3 changes



5h 25m • 3 changes



5h 13m • 3 changes



5h 23m • 3 changes



5h 13m • 3 changes



5h 25m • 3 changes



5h 13m • 3 changes



5h 23m • 3 changes



5h 13m • 3 changes



5h 25m • 3 changes



5h 13m • 3 changes



5h 23m • 3 changes
Want to know about travelling from Ayr to Middlesbrough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Ayr to Middlesbrough. However, there are services departing from Ayr station and arriving at Middlesbrough station via Glasgow Central. The journey, including transfers, takes approximately 5h 54m.
Ayr to Middlesbrough train services, operated by ScotRail, depart from Ayr station.
Ayr to Middlesbrough train services, operated by ScotRail, arrive at Darlington station.
Book your Ayr to Middlesbrough train tickets online with ScotRail, Cross Country and 2 other operators.
The distance between Ayr and Middlesbrough is 238 km. The road distance is 418 km.
You can take a train from Ayr to Middlesbrough via Glasgow Central, Edinburgh Waverley, and Darlington in around 5h 46m.