The average train between Ayr and Derby takes 7h 28m and the fastest train takes 6h 3m. There is a train service every few hours from Ayr to Derby. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Ayr and Derby. The earliest departure is at 5:15 AM in the morning, and the last departure from Ayr is at 11:05 PM which arrives into Derby at 9:40 AM. All services require a transfer at Glasgow Central and take an average of 7h 28m. The schedules shown below are for the next available departures.



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6h 26m • 3 changes



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6h 6m • 3 changes
Want to know about travelling from Ayr to Derby? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Ayr to Derby. However, there are services departing from Ayr station and arriving at Derby station via Glasgow Central. The journey, including transfers, takes approximately 7h 28m.
Ayr to Derby train services, operated by ScotRail, depart from Ayr station.
Ayr to Derby train services, operated by ScotRail, arrive at Derby station.
Book your Ayr to Derby train tickets online with ScotRail, Avanti West Coast and East Midlands Railways.
The distance between Ayr and Derby is 349.1 km. The road distance is 535 km.
You can take a train from Ayr to Derby via Glasgow Central, Warrington Bank Quay, and Crewe in around 7h 15m.