The average train between Avignon and Toulouse takes 4h 32m and the fastest train takes 3h 35m. The train service runs several times per day from Avignon to Toulouse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Avignon and Toulouse. The earliest departure is at 7:17 AM in the morning, and the last departure from Avignon is at 9:33 PM which arrives into Toulouse at 9:12 AM. All services require a transfer, and take on average 4h 32m. The schedules shown below are for the next available departures.

3h 39m • 1 change

3h 39m • 1 change

3h 41m • 1 change

4h • 1 change

3h 35m • 1 change

3h 39m • 1 change

3h 39m • 1 change

3h 41m • 1 change

3h 35m • 1 change

3h 39m • 1 change

3h 39m • 1 change

3h 41m • 1 change

3h 39m • 1 change

3h 40m • 1 change

3h 42m • 1 change
Arrives next day

15h 19m • 1 change

4h 43m • 1 change

3h 41m • 1 change

3h 42m • 1 change

3h 46m • 1 change

3h 35m • 1 change

3h 39m • 1 change

3h 39m • 1 change

3h 41m • 1 change
Want to know about travelling from Avignon to Toulouse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Avignon to Toulouse. However, there are services departing from Avignon station and arriving at Toulouse station via Nimes. The journey, including transfers, takes approximately 4h 32m.
Avignon to Toulouse train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Avignon Centre station.
Avignon to Toulouse train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Toulouse Matabiau station.
Book your Avignon to Toulouse train tickets online with Société Nationale des Chemins de fer Français (SNCF) and TGV inOui.
The distance between Avignon and Toulouse is 272.9 km. The road distance is 345 km.
You can take a train from Avignon Centre to Toulouse Matabiau via Nimes in around 4h 13m.