The average train between Amboise and Lyon takes 6h 54m and the fastest train takes 3h 25m. The train service runs several times per day from Amboise to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Amboise and Lyon. The earliest departure is at 1:19 AM at night, and the last departure from Amboise is at 10:36 PM which arrives into Lyon at 9:30 AM. All services require a transfer, and take on average 6h 54m. The schedules shown below are for the next available departures.

8h 11m • 1 change
5h 24m • 1 change
7h 56m • 1 change
5h 47m • 1 changeWant to know about travelling from Amboise to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Amboise to Lyon. However, there are services departing from St Pierre Des Corps station and arriving at Lyon Part Dieu station via Lyon Part Dieu station. The journey, including transfers, takes approximately 6h 54m.
Amboise to Lyon train services, operated by TGV inOui, depart from St Pierre Des Corps station.
Amboise to Lyon train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
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The distance between Amboise and Lyon is 348.3 km. The road distance is 418 km.
TGV inOui operates a train from St Pierre Des Corps to Lyon Part Dieu 4 times a day. Tickets cost €120–190 and the journey takes 3h 3m. Société Nationale des Chemins de fer Français (SNCF) also services this route every 4 hours.