The average train between Agen and Lyon takes 8h 35m and the fastest train takes 5h 55m. The train service runs several times per day from Agen to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Agen and Lyon. The earliest departure is at 7:25 AM in the morning, and the last departure from Agen is at 5:27 PM which arrives into Lyon at 7:23 AM. All services require a transfer, and take on average 8h 35m. The schedules shown below are for the next available departures.

5h 55m • 1 change

6h 25m • 1 change
Arrives next day

14h 57m • 1 change

5h 55m • 1 change

6h 25m • 1 change
Arrives next day

13h 56m • 1 change

5h 55m • 1 change

6h 25m • 1 change
Arrives next day

14h 57m • 1 change

5h 55m • 1 change

6h 25m • 1 change
Arrives next day

14h 57m • 1 change
Want to know about travelling from Agen to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Agen to Lyon. However, there are services departing from Agen station and arriving at Lyon station via Nimes. The journey, including transfers, takes approximately 8h 35m.
Agen to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Agen station.
Agen to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Lyon Part Dieu station.
Book your Agen to Lyon train tickets online with Société Nationale des Chemins de fer Français (SNCF), TGV inOui and Renfe Viajeros.
The distance between Agen and Lyon is 374.2 km. The road distance is 682 km.
You can take a train from Agen to Lyon Part Dieu via Nimes in around 6h 4m.