The average bus between Zurich and Rome takes 13h 49m and the fastest bus takes 12h 45m. The bus service runs several times per day from Zurich to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Zurich and Rome. The earliest departure is at 1:35 AM at night, and the last departure from Zurich is at 10:40 PM which arrives into Rome at 1:50 PM. All services require a transfer, and take on average 13h 49m. The schedules shown below are for the next available departures.

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Want to know about travelling from Zurich to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Zurich to Rome. However, there are services departing from Zurich station and arriving at Rome station via Milan. The journey, including transfers, takes approximately 13h 49m.
Zurich to Rome bus services, operated by FlixBus, depart from Zurich Bus Station.
Zurich to Rome bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Book your Zurich to Rome bus tickets online with FlixBus, Itabus S.p.A. and TTI Leonettibus SRL.
The distance between Zurich and Rome is 683.2 km. The road distance is 877 km.
You can take a bus from Zurich Bus Station to Roma, Autostazione Tiburtina via Milano, Autostazione Lampugnano in around 12h 27m.