Rome2Rio

West Chester to Chicago buses

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Trip Overview

The average bus between West Chester and Chicago takes 21h 49m and the fastest bus takes 21h 24m. The bus runs, on average, 3 times per week from West Chester to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 49m
Duration
955 mi
Distance
$187
Average price
3 times a week
Frequency

West Chester to Chicago bus times

Buses run 3 times a week between West Chester and Chicago. The earliest departure is at 9:30 PM at night, and the last departure from West Chester is at 10:30 PM which arrives into Chicago at 6:55 PM. All services require a transfer at 69th St Transit Center and take an average of 21h 49m. The schedules shown below are for the next available departures.

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    SEPTASEPTAFlixbus USA22h 24m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    SEPTASEPTAFlixbus USA21h 39m • 2 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    SEPTASEPTAFlixbus USA21h 24m • 2 changes

Frequently asked questions

Want to know about travelling from West Chester to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from West Chester to Chicago.ExpandLaunch map view
  • Distance: 955 mi
  • Duration: 21h 49m

What companies run services between West Chester, PA, USA and Chicago, IL, USA?

Flixbus USA operates a bus from Philadelphia Bus Station to Chicago Bus Station 3 times a week. Tickets cost $150–230 and the journey takes 20h.

Operators