The average bus between Wertheim and Prague takes 9h 40m and the fastest bus takes 7h 5m. The bus service runs several times per day from Wertheim to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Wertheim and Prague. The earliest departure is at 5:40 AM in the morning, and the last departure from Wertheim is at 8:45 PM which arrives into Prague at 8:55 AM. All services require a transfer at Würzburg Main Station and take an average of 9h 40m. The schedules shown below are for the next available departures.


7h 5m • 2 changes


8h 30m • 2 changes


7h 42m • 2 changes
Arrives next day


15h 27m • 2 changes


7h 5m • 2 changes


8h 30m • 2 changes


7h 42m • 2 changes
Arrives next day


12h 10m • 2 changes


9h 40m • 2 changes


8h 30m • 2 changes
Arrives next day


15h 55m • 2 changes
Want to know about travelling from Wertheim to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Wertheim to Prague. However, there are services departing from Wertheim station and arriving at Prague station via Würzburg, Hauptbahnhof ZOB. The journey, including transfers, takes approximately 9h 40m.
Wertheim to Prague bus services, operated by VerkehrsGesellschaft Main-Tauber mbH, depart from Wertheim, ZOB station.
Wertheim to Prague bus services, operated by VerkehrsGesellschaft Main-Tauber mbH, arrive at Prague station.
The distance between Wertheim and Prague is 353.5 km. The road distance is 440 km.
You can take a bus from Wertheim, ZOB to Prague via Würzburg Main Station and Nuremberg central bus station in around 7h 46m.