The average bus between Uxbridge and Manchester takes 5h 49m and the fastest bus takes 5h 10m. There is a bus service every few hours from Uxbridge to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Uxbridge and Manchester. The earliest departure is at 12:35 AM at night, and the last departure from Uxbridge is at 8:05 PM which arrives into Manchester at 1:15 AM. All services require a transfer at Finchley Road station and take an average of 5h 49m. The schedules shown below are for the next available departures.


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Want to know about travelling from Uxbridge to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Uxbridge to Manchester. However, there are services departing from Uxbridge station and arriving at Manchester station via Shudehill Interchange. The journey, including transfers, takes approximately 5h 49m.
Uxbridge to Manchester bus services, operated by Arriva UK, depart from Finchley Road / O2 Centre station.
Uxbridge to Manchester bus services, operated by Arriva UK, arrive at Shudehill Interchange station.
The distance between Uxbridge and Manchester is 245.5 km. The road distance is 339 km.
FlixBus operates a bus from Finchley Road / O2 Centre to Shudehill Interchange hourly. Tickets cost £21–35 and the journey takes 4h 30m.