The average bus between Times Square and Natick takes 6h 16m and the fastest bus takes 5h 30m. The bus service runs several times per day from Times Square to Natick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Times Square and Natick. The earliest departure is at 1:00 AM at night, and the last departure from Times Square is at 11:30 PM which arrives into Natick at 5:47 AM. All services require a transfer at South Station and take an average of 6h 16m. The schedules shown below are for the next available departures.
Arrives next day

6h 16m • 1 change
Arrives next day

6h 17m • 1 change

6h 46m • 1 change

6h 42m • 1 change

6h 2m • 1 change

5h 30m • 1 change

6h 46m • 1 change

6h 42m • 1 change

6h 2m • 1 change

5h 30m • 1 change
Want to know about travelling from Times Square to Natick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Times Square to Natick. However, there are services departing from Times Square station and arriving at Natick station via South Station station. The journey, including transfers, takes approximately 6h 16m.
Times Square to Natick bus services, operated by Peter Pan Bus Lines, depart from Port Authority Bus Terminal station.
Times Square to Natick bus services, operated by Peter Pan Bus Lines, arrive at South Station.
The distance between Times Square and Natick is 277.5 km. The road distance is 373 km.
Peter Pan Bus Lines operates a bus from Port Authority Bus Terminal to South Station every 2 hours. Tickets cost $40–95 and the journey takes 4h 35m. Greyhound USA also services this route hourly.