The St. Regis Rome to Florence Buses

The St. Regis Rome to Florence buses

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Trip Overview

The average bus between The St. Regis Rome and Florence takes 4h and the fastest bus takes 3h 40m. There is a bus service every few hours from The St. Regis Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h
Duration: 281 km
Distance: €30
Average price: Hourly
Frequency

Bus

best

Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus 510 / ...

4h 12m

€16–44

The St. Regis Rome to Florence bus times

Buses run hourly between The St. Regis Rome and Florence. The earliest departure is at 5:57 AM in the morning, and the last departure from The St. Regis Rome is at 10:26 PM which arrives into Florence at 2:10 AM. All services require a transfer at L.Go S. Susanna and take an average of 4h. The schedules shown below are for the next available departures.

Departing Friday, October 16, 2026

6:09 AM → 10:15 AM
4h 5m • 1 change
7:27 AM → 11:10 AM
3h 42m • 1 change
7:49 AM → 11:45 AM
3h 55m • 1 change
8:12 AM → 12:15 PM
4h 2m • 1 change
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Departing Saturday, October 17, 2026

6:03 AM → 10:15 AM
4h 11m • 1 change
7:27 AM → 11:10 AM
3h 43m • 1 change
7:46 AM → 11:45 AM
3h 59m • 1 change
8:14 AM → 12:15 PM
4h • 1 change
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Departing Sunday, October 18, 2026

5:57 AM → 10:15 AM
4h 17m • 1 change
7:18 AM → 11:10 AM
3h 51m • 1 change
7:39 AM → 11:45 AM
4h 5m • 1 change
8:18 AM → 12:15 PM
3h 56m • 1 change
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Frequently asked questions

Want to know about travelling from The St. Regis Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between The St. Regis Rome, Italy and Florence, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station hourly. Tickets cost €22–35 and the journey takes 3h 15m. Three other operators also service this route.

Operators