The St. Regis Rome to Florence Buses

The St. Regis Rome to Florence buses

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Trip Overview

The average bus between The St. Regis Rome and Florence takes 4h 1m and the fastest bus takes 3h 40m. There is a bus service every few hours from The St. Regis Rome to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 1m
Duration: 281 km
Distance: €34
Average price: Hourly
Frequency

Bus

best

Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus 510 / ...

4h 13m

€16–48

The St. Regis Rome to Florence bus times

Buses run hourly between The St. Regis Rome and Florence. The earliest departure is at 5:57 AM in the morning, and the last departure from The St. Regis Rome is at 10:29 PM which arrives into Florence at 2:10 AM. All services require a transfer at L.Go S. Susanna and take an average of 4h 1m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

6:09 AM → 10:15 AM
4h 5m • 1 change
7:27 AM → 11:10 AM
3h 42m • 1 change
7:49 AM → 11:45 AM
3h 55m • 1 change
8:12 AM → 12:30 PM
4h 17m • 1 change
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Departing Friday, November 6, 2026

6:09 AM → 10:15 AM
4h 5m • 1 change
7:27 AM → 11:10 AM
3h 42m • 1 change
7:49 AM → 11:45 AM
3h 55m • 1 change
8:12 AM → 12:30 PM
4h 17m • 1 change
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Departing Saturday, November 7, 2026

6:03 AM → 10:15 AM
4h 11m • 1 change
7:27 AM → 11:10 AM
3h 43m • 1 change
7:46 AM → 11:45 AM
3h 59m • 1 change
8:14 AM → 12:30 PM
4h 15m • 1 change
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Departing Sunday, November 8, 2026

5:57 AM → 10:15 AM
4h 17m • 1 change
7:18 AM → 11:10 AM
3h 51m • 1 change
7:39 AM → 11:45 AM
4h 5m • 1 change
8:18 AM → 12:30 PM
4h 11m • 1 change
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Departing Monday, November 9, 2026

6:09 AM → 10:15 AM
4h 5m • 1 change
7:27 AM → 11:10 AM
3h 42m • 1 change
7:49 AM → 11:45 AM
3h 55m • 1 change
8:12 AM → 12:30 PM
4h 17m • 1 change
Show more

Departing Tuesday, November 10, 2026

6:09 AM → 10:15 AM
4h 5m • 1 change
7:27 AM → 11:10 AM
3h 42m • 1 change
7:49 AM → 11:45 AM
3h 55m • 1 change
8:12 AM → 12:30 PM
4h 17m • 1 change
Show more

Departing Wednesday, November 11, 2026

7:27 AM → 11:10 AM
3h 42m • 1 change
7:49 AM → 11:45 AM
3h 55m • 1 change
8:12 AM → 12:30 PM
4h 17m • 1 change
9:29 AM → 1:25 PM
3h 55m • 1 change
Show more

Frequently asked questions

Want to know about travelling from The St. Regis Rome to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.