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Tennessee to St. Louis buses

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Trip Overview

The average bus between Tennessee and St. Louis takes 7h 13m and the fastest bus takes 6h 55m. The bus service runs several times per day from Tennessee to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 13m
Duration
318 mi
Distance
$72
Average price
3 times a day
Frequency

Tennessee to St. Louis bus times

Buses run 3 times a day between Tennessee and St. Louis. The earliest departure is at 1:15 AM at night, and the last departure from Tennessee is at 2:35 PM which arrives into St. Louis at 9:30 PM. All services require a transfer at Fulton Station Outbound and take an average of 7h 13m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    WeGo TransitGreyhound USA6h 55m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    WeGo TransitFlixbus USA8h 5m • 1 change
  •  → 

    WeGo TransitGreyhound USA6h 55m • 1 change
  •  → 

    WeGo TransitGreyhound USA6h 55m • 1 change

Departing Friday, November 13, 2026

  •  → 

    WeGo TransitFlixbus USA8h 5m • 1 change
  •  → 

    WeGo TransitGreyhound USA6h 55m • 1 change
  •  → 

    WeGo TransitGreyhound USA6h 55m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    WeGo TransitFlixbus USA8h 5m • 1 change
  •  → 

    WeGo TransitGreyhound USA6h 55m • 1 change
  •  → 

    WeGo TransitGreyhound USA7h • 1 change

Departing Sunday, November 15, 2026

  •  → 

    WeGo TransitFlixbus USA8h 5m • 1 change
  •  → 

    WeGo TransitGreyhound USA6h 55m • 1 change
  •  → 

    WeGo TransitGreyhound USA7h • 1 change

Departing Monday, November 16, 2026

  •  → 

    WeGo TransitFlixbus USA8h 5m • 1 change
  •  → 

    WeGo TransitGreyhound USA6h 55m • 1 change
  •  → 

    WeGo TransitGreyhound USA6h 55m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    WeGo TransitGreyhound USA6h 55m • 1 change
  •  → 

    WeGo TransitGreyhound USA6h 55m • 1 change

Frequently asked questions

Want to know about travelling from Tennessee to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Tennessee to St. Louis.ExpandLaunch map view
  • Distance: 318.1 mi
  • Duration: 7h 13m

What companies run services between Tennessee, USA and St. Louis, MO, USA?

Greyhound USA operates a bus from Nashville Bus Station to St Louis Bus Station twice daily. Tickets cost $55–85 and the journey takes 6h 40m. Flixbus USA also services this route 5 times a week.

Operators