The average bus between St. Louis and Keystone, CO takes 27h 5m and the fastest bus takes 20h 15m. There is at least one bus per day from St. Louis to Keystone, CO. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between St. Louis and Keystone, CO. The earliest departure is at 5:15 PM in the evening, and the last departure from St. Louis is at 11:45 PM which arrives into Keystone, CO at 7:00 AM. All services require a transfer at Denver Union Station and take an average of 27h 5m. The schedules shown below are for the next available departures.
Arrives next day


19h 15m • 2 changes
Arrives +2 days


31h 15m • 2 changes
Arrives next day


19h 15m • 2 changes
Arrives +2 days


31h 15m • 2 changes
Want to know about travelling from St. Louis to Keystone, CO? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from St. Louis to Keystone, CO. However, there are services departing from St. Louis station and arriving at Keystone, CO station via Denver Union Station station. The journey, including transfers, takes approximately 27h 5m.
St. Louis to Keystone, CO bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Keystone, CO bus services, operated by Greyhound USA, arrive at Frisco Transit Center station.
The distance between St. Louis and Keystone, CO is 1,361.2 km. The road distance is 1,522 km.
You can take a bus from St Louis Bus Station to River Run via Denver Union Station, Union Station Gate B19, Frisco Transit Center, and Frisco Transfer Center in around 20h 57m.