Rome2Rio

St. Louis to Islamorada buses

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Trip Overview

The bus between St. Louis and Islamorada takes 45h. The bus runs, on average, 5 times per week from St. Louis to Islamorada. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

45h
Duration
1,325 mi
Distance
$285
Average price
5 times a week
Frequency

St. Louis to Islamorada bus times

Buses run 5 times a week between St. Louis and Islamorada. The service departs St. Louis at 9:00 AM in the morning, which arrives into Islamorada at 07:00:00. All services require a transfer at Atlanta Bus Station and take an average of 45h. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives +2 days

    Greyhound USAFlixbus USAGreyhound USA45h • 2 changes

Departing Friday, November 13, 2026

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    Arrives +2 days

    Greyhound USAFlixbus USAGreyhound USA45h • 2 changes

Departing Saturday, November 14, 2026

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    Arrives +2 days

    Greyhound USAFlixbus USAGreyhound USA45h • 2 changes

Departing Sunday, November 15, 2026

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    Arrives +2 days

    Greyhound USAFlixbus USAGreyhound USA45h • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAGreyhound USA45h • 2 changes

Frequently asked questions

Want to know about travelling from St. Louis to Islamorada? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Islamorada.ExpandLaunch map view
  • Distance: 1,324.6 mi
  • Duration: 45h

What companies run services between St. Louis, MO, USA and Islamorada, FL, USA?

You can take a bus from St Louis Bus Station to Islamorada via Atlanta Bus Station and Miami Airport Station in around 29h 5m.

Operators