The average bus between Springfield and Des Moines takes 43h 14m and the fastest bus takes 39h 35m. The bus service runs several times per day from Springfield to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Springfield and Des Moines. The earliest departure is at 4:10 AM at night, and the last departure from Springfield is at 4:00 PM which arrives into Des Moines at 2:35 PM. All services require a transfer at New York Midtown and take an average of 43h 14m. The schedules shown below are for the next available departures.
Arrives next day


38h 45m • 2 changes
Arrives +2 days


46h 35m • 2 changes
Arrives next day


38h 35m • 2 changes
Arrives +2 days


46h 35m • 2 changes
Arrives next day


38h 35m • 2 changes
Arrives +2 days


46h 35m • 2 changes
Want to know about travelling from Springfield to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Springfield to Des Moines. However, there are services departing from Springfield station and arriving at Des Moines station via New York Midtown. The journey, including transfers, takes approximately 43h 14m.
Springfield to Des Moines bus services, operated by Flixbus USA, depart from Springfield Union Station.
Springfield to Des Moines bus services, operated by Flixbus USA, arrive at Des Moines station.
Book your Springfield to Des Moines bus tickets online with Flixbus USA and Greyhound USA.
The distance between Springfield and Des Moines is 1,737.5 km. The road distance is 2,190 km.
You can take a bus from Springfield Union Station to Des Moines via New York Midtown and Chicago Bus Station in around 28h 5m.