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Springfield to Des Moines buses

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Trip Overview

The average bus between Springfield and Des Moines takes 45h 43m and the fastest bus takes 39h 35m. There is at least one bus per day from Springfield to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

45h 43m
Duration
1,474 mi
Distance
$287
Average price
Once daily
Frequency

Springfield to Des Moines bus times

Buses run once daily between Springfield and Des Moines. The earliest departure is at 4:10 AM at night, and the last departure from Springfield is at 11:35 PM which arrives into Des Moines at 6:45 PM. All services require a transfer at New York Midtown and take an average of 45h 43m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA44h 10m • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA47h 35m • 2 changes
  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA44h 10m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA47h 35m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAGreyhound USA39h 35m • 2 changes
  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA47h 35m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA47h 35m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    Flixbus USAFlixbus USAGreyhound USA47h 35m • 2 changes

Frequently asked questions

Want to know about travelling from Springfield to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Springfield to Des Moines.ExpandLaunch map view
  • Distance: 1,474.5 mi
  • Duration: 45h 43m

What companies run services between Springfield, MA, USA and Des Moines, IA, USA?

You can take a bus from Springfield Union Station to Des Moines via New York Midtown and Chicago Bus Station in around 31h 35m.

Operators