The average bus between Southampton and Ruislip takes 3h 7m and the fastest bus takes 2h 40m. There is a bus service every few hours from Southampton to Ruislip. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Southampton and Ruislip. The earliest departure is at 2:05 AM at night, and the last departure from Southampton is at 8:30 PM which arrives into Ruislip at 11:10 PM. All services require a transfer, and take on average 3h 7m. The schedules shown below are for the next available departures.

2h 58m • 1 change

2h 55m • 1 change

3h 10m • 1 change

3h 10m • 1 change

2h 52m • 1 change

2h 44m • 1 change

3h 8m • 1 change

2h 56m • 1 change

2h 52m • 1 change

2h 44m • 1 change

3h 8m • 1 change

2h 56m • 1 change

2h 52m • 1 change

3h 8m • 1 change

3h 33m • 1 change

3h 29m • 1 change
Want to know about travelling from Southampton to Ruislip? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Southampton to Ruislip. However, there are services departing from Southampton station and arriving at Ruislip station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 3h 7m.
Southampton to Ruislip bus services, operated by National Express, depart from Coach Station.
Southampton to Ruislip bus services, operated by National Express, arrive at Midcroft station.
The distance between Southampton and Ruislip is 101 km. The road distance is 126 km.
You can take a bus from Coach Station to Midcroft via Heathrow Central Bus Station in around 2h 55m.