The average bus between Southampton and Luton takes 3h 59m and the fastest bus takes 3h. There is a bus service every few hours from Southampton to Luton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Southampton and Luton. The earliest departure is at 4:15 AM at night, and the last departure from Southampton is at 8:30 PM which arrives into Luton at 12:05 AM. All services require a transfer, and take on average 3h 59m. The schedules shown below are for the next available departures.

3h 45m • 1 change

3h 50m • 1 change

3h 45m • 1 change
Arrives next day

3h 35m • 1 change

3h • 1 change

3h 50m • 1 change

4h 10m • 1 change

4h 20m • 1 change

3h • 1 change

3h 50m • 1 change

4h 10m • 1 change

4h 20m • 1 change

3h 35m • 1 change

4h 10m • 1 change

4h 30m • 1 change

4h 20m • 1 change

4h 25m • 1 change

4h 5m • 1 change

3h 35m • 1 change

3h 15m • 1 change
Want to know about travelling from Southampton to Luton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Southampton to Luton. However, there are services departing from Southampton station and arriving at Luton station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 3h 59m.
Southampton to Luton bus services, operated by National Express, depart from Coach Station.
Southampton to Luton bus services, operated by National Express, arrive at Luton Station Interchange.
Book your Southampton to Luton bus tickets online with National Express.
The distance between Southampton and Luton is 128.3 km. The road distance is 169 km.
You can take a bus from Coach Station to Luton Station Interchange via Heathrow Central Bus Station in around 3h 30m.