The average bus between Soho and Slough takes 1h 28m and the fastest bus takes 1h 7m. There is an hourly bus service from Soho to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Soho and Slough. The earliest departure is at 6:28 AM in the morning, and the last departure from Soho is at 11:21 PM which arrives into Slough at 12:32 AM. All services require a transfer, and take on average 1h 28m. The schedules shown below are for the next available departures.

1h 23m • 1 change

1h 18m • 1 change

1h 20m • 1 change

1h 27m • 1 change

1h 23m • 1 change

1h 18m • 1 change

1h 20m • 1 change

1h 27m • 1 change

1h 12m • 1 change

1h 14m • 1 change

1h 26m • 1 change

1h 31m • 1 change
Want to know about travelling from Soho to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Soho to Slough. However, there are services departing from Soho station and arriving at Slough station via High Street Kensington Station station. The journey, including transfers, takes approximately 1h 28m.
Soho to Slough bus services, operated by Metroline Travel, depart from Piccadilly Circus station.
Soho to Slough bus services, operated by Metroline Travel, arrive at Wellington Street Stop H station.
The distance between Soho and Slough is 31.9 km. The road distance is 34 km.
You can take a bus from Piccadilly Circus to Wellington Street Stop H via High Street Kensington Station in around 1h 54m.