The average bus between Slough and Southwark takes 1h 51m and the fastest bus takes 1h 14m. There is an hourly bus service from Slough to Southwark. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Slough and Southwark. The earliest departure is at 5:42 AM in the morning, and the last departure from Slough is at 10:00 PM which arrives into Southwark at 11:25 PM. All services require a transfer, and take on average 1h 51m. The schedules shown below are for the next available departures.

2h 1m • 1 change

1h 57m • 1 change

1h 51m • 1 change

1h 54m • 1 change

1h 22m • 1 change

1h 47m • 1 change

2h 2m • 1 change

2h 8m • 1 change

1h 14m • 1 change

1h 22m • 1 change

1h 33m • 1 change

1h 40m • 1 change
Want to know about travelling from Slough to Southwark? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Southwark. However, there are services departing from Slough station and arriving at Southwark station via Green Line Coach Station station. The journey, including transfers, takes approximately 1h 51m.
Slough to Southwark bus services, operated by Reading Buses, depart from Wellington Street Stop C station.
Slough to Southwark bus services, operated by Reading Buses, arrive at Waterloo Station/Upper Taxi Rd.
The distance between Slough and Southwark is 34.1 km. The road distance is 37 km.
You can take a bus from Wellington Street Stop C to Waterloo Station/Upper Taxi Rd via Eccleston Bridge in around 1h 48m.