Bus Slough to Manchester from £23 | Tickets & Timetables

Trip Overview

The average bus between Slough and Manchester takes 5h 55m and the fastest bus takes 5h 28m. The bus service runs several times per day from Slough to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 55m
Duration: 205 mi
Distance: £23
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from London Heathrow Airport to Manchester, Shudehill Interchangebus Uk980 / ...

6h 43m

£19–35

Slough to Manchester bus times

Buses run every 4 hours between Slough and Manchester. The earliest departure is at 12:02 AM at night, and the last departure from Slough is at 11:32 PM which arrives into Manchester at 5:30 AM. All services require a transfer at Heathrow Central Bus Station and take an average of 5h 55m. The schedules shown below are for the next available departures.

Departing Monday, May 18, 2026

7:43 AM → 1:50 PM
6h 7m • 1 change
1:27 PM → 7:30 PM
6h 3m • 1 change
3:14 PM → 9:30 PM
6h 16m • 1 change
10:02 PM → 3:30 AM
Arrives next day
5h 28m • 1 change

Departing Tuesday, May 19, 2026

12:02 AM → 5:30 AM
5h 28m • 1 change
6:00 AM → 11:50 AM
5h 50m • 1 change
7:43 AM → 1:50 PM
6h 7m • 1 change
1:27 PM → 7:30 PM
6h 3m • 1 change
Show more

Departing Wednesday, May 20, 2026

12:02 AM → 5:30 AM
5h 28m • 1 change
6:00 AM → 11:50 AM
5h 50m • 1 change
7:43 AM → 1:50 PM
6h 7m • 1 change
1:27 PM → 7:30 PM
6h 3m • 1 change
Show more

Departing Thursday, May 21, 2026

12:02 AM → 5:30 AM
5h 28m • 1 change
6:00 AM → 11:50 AM
5h 50m • 1 change
7:43 AM → 1:50 PM
6h 7m • 1 change
1:27 PM → 7:30 PM
6h 3m • 1 change
Show more

Departing Friday, May 22, 2026

12:02 AM → 5:30 AM
5h 28m • 1 change
6:00 AM → 11:50 AM
5h 50m • 1 change
7:43 AM → 1:50 PM
6h 7m • 1 change
1:27 PM → 7:30 PM
6h 3m • 1 change
Show more

Departing Saturday, May 23, 2026

12:02 AM → 5:30 AM
5h 28m • 1 change
5:58 AM → 11:50 AM
5h 52m • 1 change
7:39 AM → 1:50 PM
6h 11m • 1 change
1:14 PM → 7:30 PM
6h 16m • 1 change
Show more

Departing Sunday, May 24, 2026

12:02 AM → 5:30 AM
5h 28m • 1 change
5:57 AM → 11:50 AM
5h 53m • 1 change
7:38 AM → 1:50 PM
6h 12m • 1 change
1:14 PM → 7:30 PM
6h 16m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Slough to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.