The average bus between Slough and Manchester takes 6h 1m and the fastest bus takes 5h 19m. There is a bus service every few hours from Slough to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Slough and Manchester. The earliest departure is at 12:02 AM at night, and the last departure from Slough is at 7:50 PM which arrives into Manchester at 1:15 AM. All services require a transfer at Heathrow Central Bus Station and take an average of 6h 1m. The schedules shown below are for the next available departures.


6h 21m • 2 changes


5h 53m • 2 changes


5h 55m • 2 changes


6h 16m • 2 changes


6h 3m • 2 changes


6h 7m • 2 changes


6h 56m • 2 changes


6h 6m • 2 changes


6h 3m • 2 changes


6h 7m • 2 changes


6h 56m • 2 changes


6h 6m • 2 changes


6h 3m • 2 changes


6h 7m • 2 changes


6h 56m • 2 changes


6h 6m • 2 changes


6h 3m • 2 changes


6h 7m • 2 changes


6h 56m • 2 changes


6h 6m • 2 changes
Want to know about travelling from Slough to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Manchester. However, there are services departing from Slough station and arriving at Manchester station via Birmingham Coach Station station. The journey, including transfers, takes approximately 6h 1m.
Slough to Manchester bus services, operated by First Berkshire & The Thames Valley, depart from Heathrow Central Bus Station.
Slough to Manchester bus services, operated by First Berkshire & The Thames Valley, arrive at Manchester Central Coach Station.
Book your Slough to Manchester bus tickets online with First Berkshire & The Thames Valley and National Express.
The distance between Slough and Manchester is 245.8 km. The road distance is 337 km.
You can take a bus from Wellington Street Stop B to Manchester Central Coach Station via Heathrow Central Bus Station and Birmingham Coach Station in around 5h 54m.