The average bus between Slough and Lewes takes 3h 26m and the fastest bus takes 2h 58m. There is a bus service every few hours from Slough to Lewes. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Slough and Lewes. The earliest departure is at 12:00 AM at night, and the last departure from Slough is at 10:00 PM which arrives into Lewes at 1:14 AM. All services require a transfer at Heathrow Terminal 5 and take an average of 3h 26m. The schedules shown below are for the next available departures.


3h 24m • 2 changes


3h 33m • 2 changes


3h 24m • 2 changes
Arrives next day


3h 14m • 2 changes


3h 38m • 2 changes


3h • 2 changes


3h 16m • 2 changes


3h 29m • 2 changes


3h 38m • 2 changes


3h • 2 changes


3h 16m • 2 changes


3h 29m • 2 changes


3h 38m • 2 changes


3h • 2 changes


3h 16m • 2 changes


3h 29m • 2 changes
Want to know about travelling from Slough to Lewes? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Lewes. However, there are services departing from Slough station and arriving at Lewes station via Old Steine. The journey, including transfers, takes approximately 3h 26m.
Slough to Lewes bus services, operated by Thames Valley Buses, depart from Heathrow Terminal 5 station.
Slough to Lewes bus services, operated by Thames Valley Buses, arrive at Old Steine station.
Book your Slough to Lewes bus tickets online with Thames Valley Buses, National Express and 2 other operators.
The distance between Slough and Lewes is 82.3 km. The road distance is 131 km.
National Express operates a bus from Heathrow Terminal 5 to Old Steine hourly. Tickets cost £12–29 and the journey takes 2h.