The average bus between Slough and Gloucester takes 3h 26m and the fastest bus takes 3h 11m. The bus service runs several times per day from Slough to Gloucester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Slough and Gloucester. The earliest departure is at 7:00 AM in the morning, and the last departure from Slough is at 11:32 PM which arrives into Gloucester at 3:00 AM. All services require a transfer, and take on average 3h 26m. The schedules shown below are for the next available departures.

3h 26m • 1 change

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3h 19m • 1 change
Arrives next day

3h 28m • 1 change

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3h 49m • 1 change

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3h 16m • 1 change

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3h 19m • 1 change

3h 24m • 1 change

3h 16m • 1 change

3h 29m • 1 change

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3h 19m • 1 change
Want to know about travelling from Slough to Gloucester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Gloucester. However, there are services departing from Slough station and arriving at Gloucester station via Transport Hub. The journey, including transfers, takes approximately 3h 26m.
Slough to Gloucester bus services, operated by First Berkshire & The Thames Valley, depart from Heathrow Central Bus Station.
Slough to Gloucester bus services, operated by First Berkshire & The Thames Valley, arrive at Transport Hub station.
Book your Slough to Gloucester bus tickets online with First Berkshire & The Thames Valley and National Express.
The distance between Slough and Gloucester is 120.3 km. The road distance is 179 km.
National Express operates a bus from Heathrow Central Bus Station to Transport Hub hourly. Tickets cost £19–50 and the journey takes 2h 45m.