The average bus between Slough and Exeter takes 4h 25m and the fastest bus takes 3h 59m. The bus service runs several times per day from Slough to Exeter. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Slough and Exeter. The earliest departure is at 7:29 AM in the morning, and the last departure from Slough is at 10:32 PM which arrives into Exeter at 3:00 AM. All services require a transfer, and take on average 4h 25m. The schedules shown below are for the next available departures.

4h 41m • 1 change

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4h 24m • 1 change

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Want to know about travelling from Slough to Exeter? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Exeter. However, there are services departing from Slough station and arriving at Exeter station via Bampfylde Street. The journey, including transfers, takes approximately 4h 25m.
Slough to Exeter bus services, operated by First Berkshire & The Thames Valley, depart from Heathrow Central Bus Station.
Slough to Exeter bus services, operated by First Berkshire & The Thames Valley, arrive at Bampfylde Street station.
Book your Slough to Exeter bus tickets online with First Berkshire & The Thames Valley and National Express.
The distance between Slough and Exeter is 222.5 km. The road distance is 266 km.
National Express operates a bus from Heathrow Central Bus Station to Bampfylde Street every 2 hours. Tickets cost £30–70 and the journey takes 3h 50m.