The average bus between Slough and Bristol takes 2h 53m and the fastest bus takes 2h 33m. There is a bus service every few hours from Slough to Bristol. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Slough and Bristol. The earliest departure is at 2:32 AM at night, and the last departure from Slough is at 11:32 PM which arrives into Bristol at 2:35 AM. All services require a transfer, and take on average 2h 53m. The schedules shown below are for the next available departures.

3h 5m • 1 change

2h 59m • 1 change

2h 55m • 1 change

3h • 1 change

2h 43m • 1 change

2h 51m • 1 change

2h 50m • 1 change

3h 1m • 1 change

2h 43m • 1 change

2h 51m • 1 change

2h 50m • 1 change

3h 1m • 1 change

2h 43m • 1 change

2h 51m • 1 change

2h 50m • 1 change

3h 1m • 1 change
Want to know about travelling from Slough to Bristol? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Bristol. However, there are services departing from Slough station and arriving at Bristol station via Bus Station station. The journey, including transfers, takes approximately 2h 53m.
Slough to Bristol bus services, operated by First Berkshire & The Thames Valley, depart from Heathrow Central Bus Station.
Slough to Bristol bus services, operated by First Berkshire & The Thames Valley, arrive at Bus Station.
Book your Slough to Bristol bus tickets online with First Berkshire & The Thames Valley and National Express.
The distance between Slough and Bristol is 138.7 km. The road distance is 179 km.
National Express operates a bus from Heathrow Central Bus Station to Bus Station hourly. Tickets cost £19–50 and the journey takes 2h 5m.