The average bus between Slough and Bristol takes 2h 46m and the fastest bus takes 2h 27m. There is a bus service every few hours from Slough to Bristol. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Slough and Bristol. The earliest departure is at 12:02 AM at night, and the last departure from Slough is at 10:02 PM which arrives into Bristol at 12:55 AM. All services require a transfer at Heathrow Central Bus Station and take an average of 2h 46m. The schedules shown below are for the next available departures.

2h 44m • 1 change

2h 46m • 1 change

2h 52m • 1 change

2h 46m • 1 change

2h 38m • 1 change

2h 40m • 1 change

2h 45m • 1 change

2h 43m • 1 change

2h 38m • 1 change

2h 40m • 1 change

2h 45m • 1 change

2h 43m • 1 change

2h 38m • 1 change

2h 35m • 1 change

2h 45m • 1 change

2h 43m • 1 change
Want to know about travelling from Slough to Bristol? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Bristol. However, there are services departing from Slough station and arriving at Bristol station via Heathrow Central Bus Station station. The journey, including transfers, takes approximately 2h 46m.
Slough to Bristol bus services, operated by First Berkshire & The Thames Valley, depart from Wellington Street Stop B station.
Slough to Bristol bus services, operated by First Berkshire & The Thames Valley, arrive at Bristol Bus Station.
Book your Slough to Bristol bus tickets online with First Berkshire & The Thames Valley and FlixBus.
The distance between Slough and Bristol is 138.7 km. The road distance is 179 km.
You can take a bus from Wellington Street Stop B to Bristol Bus Station via Heathrow Central Bus Station and London Heathrow Airport in around 3h 16m.