The average bus between Slough and Brighton takes 2h 30m and the fastest bus takes 2h 15m. There is a bus service every few hours from Slough to Brighton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Slough and Brighton. The earliest departure is at 12:00 AM at night, and the last departure from Slough is at 11:00 PM which arrives into Brighton at 1:25 AM. All services require a transfer, and take on average 2h 30m. The schedules shown below are for the next available departures.

2h 35m • 1 change

2h 15m • 1 change

2h 20m • 1 change

2h 35m • 1 change

2h 35m • 1 change

2h 15m • 1 change

2h 20m • 1 change

2h 35m • 1 change

2h 35m • 1 change

2h 15m • 1 change

2h 20m • 1 change

2h 35m • 1 change
Want to know about travelling from Slough to Brighton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Brighton. However, there are services departing from Slough station and arriving at Brighton station via Preston Circus. The journey, including transfers, takes approximately 2h 30m.
Slough to Brighton bus services, operated by Thames Valley Buses, depart from Heathrow Terminal 5 station.
Slough to Brighton bus services, operated by Thames Valley Buses, arrive at Preston Circus station.
Book your Slough to Brighton bus tickets online with Thames Valley Buses, National Express and 2 other operators.
The distance between Slough and Brighton is 82.1 km. The road distance is 115 km.
National Express operates a bus from Heathrow Terminal 5 to Preston Circus hourly. Tickets cost £12–29 and the journey takes 1h 47m. FlixBus also services this route 4 times a day.