The average bus between Slough and Brighton takes 2h 36m and the fastest bus takes 2h 23m. There is a bus service every few hours from Slough to Brighton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Slough and Brighton. The earliest departure is at 3:24 AM at night, and the last departure from Slough is at 10:54 PM which arrives into Brighton at 1:25 AM. All services require a transfer, and take on average 2h 36m. The schedules shown below are for the next available departures.

2h 38m • 1 change

2h 23m • 1 change
Arrives next day

2h 41m • 1 change
Arrives next day

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2h 26m • 1 change

2h 41m • 1 change

2h 37m • 1 change

2h 51m • 1 change

2h 26m • 1 change

2h 41m • 1 change

2h 37m • 1 change

2h 51m • 1 change

2h 26m • 1 change

2h 41m • 1 change

2h 37m • 1 change
Want to know about travelling from Slough to Brighton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Brighton. However, there are services departing from Slough station and arriving at Brighton station via Heathrow Terminal 5. The journey, including transfers, takes approximately 2h 36m.
Slough to Brighton bus services, operated by Thames Valley Buses, depart from Landmark Place station.
Slough to Brighton bus services, operated by Thames Valley Buses, arrive at Preston Circus station.
Book your Slough to Brighton bus tickets online with Thames Valley Buses, National Express and FlixBus.
The distance between Slough and Brighton is 82.1 km. The road distance is 112 km.
You can take a bus from Landmark Place to Preston Circus via Heathrow Terminal 5 in around 2h 37m.