The average bus between Sistine Chapel and Milan takes 10h 13m and the fastest bus takes 7h 6m. The bus service runs several times per day from Sistine Chapel to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Sistine Chapel and Milan. The earliest departure is at 12:09 AM at night, and the last departure from Sistine Chapel is at 7:12 PM which arrives into Milan at 5:15 AM. All services require a transfer at Emo/Bragadin and take an average of 10h 13m. The schedules shown below are for the next available departures.


10h 15m • 2 changes


10h 37m • 2 changes
Arrives next day


10h 2m • 2 changes


10h 15m • 2 changes


7h 6m • 2 changes


10h 42m • 2 changes
Arrives next day


10h 4m • 2 changes


11h 35m • 2 changes


8h 56m • 2 changes


10h 54m • 2 changes
Arrives next day


10h 11m • 2 changes
Want to know about travelling from Sistine Chapel to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sistine Chapel to Milan. However, there are services departing from Sistine Chapel station and arriving at Milan station via Firenze. The journey, including transfers, takes approximately 10h 13m.
Sistine Chapel to Milan bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma station.
Sistine Chapel to Milan bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Milano, San Donato M3 station.
The distance between Sistine Chapel and Milan is 475 km. The road distance is 580 km.
You can take a vehicle from Sistine Chapel to Milano, San Donato M3 via Emo/Bragadin, Roma, and Florence Villa Constanza Bus Station in around 8h 55m.