The average bus between Sistine Chapel and Colosseum takes 24 min and the fastest bus takes 15 min. The bus runs at least 3 times per hour from Sistine Chapel to Colosseum. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 20 minutes between Sistine Chapel and Colosseum. The earliest departure is at 5:28 AM in the morning, and the last departure from Sistine Chapel is at 11:50 PM which arrives into Colosseum at 12:20 AM. All services require a transfer at Cavalleggeri/S. Pietro and take an average of 24 min. The schedules shown below are for the next available departures.

17 min • 1 change

23 min • 1 change

22 min • 1 change

18 min • 1 change
Want to know about travelling from Sistine Chapel to Colosseum? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sistine Chapel to Colosseum. However, there are services departing from Sistine Chapel station and arriving at Colosseum station via P.Za Venezia. The journey, including transfers, takes approximately 24 min.
Sistine Chapel to Colosseum bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Cavalleggeri/S. Pietro station.
Sistine Chapel to Colosseum bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Colosseo/Fori Imperiali station.
The distance between Sistine Chapel and Colosseum is 3.4 km. The road distance is 5 km.
You can take a vehicle from Sistine Chapel to Colosseum via Cavalleggeri/S. Pietro, P.Za Venezia, Fori Imperiali/Campidoglio, and Colosseo/Fori Imperiali in around 32 min.