The average bus between Siena and Palestrina takes 4h 52m and the fastest bus takes 4h 6m. The bus service runs several times per day from Siena to Palestrina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Siena and Palestrina. The earliest departure is at 5:35 AM in the morning, and the last departure from Siena is at 10:25 PM which arrives into Palestrina at 7:51 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 52m. The schedules shown below are for the next available departures.

4h 10m • 1 change

4h 31m • 1 change

4h 9m • 1 change

4h 6m • 1 change

4h 10m • 1 change

4h 31m • 1 change

4h 9m • 1 change

4h 6m • 1 change

4h 10m • 1 change

4h 31m • 1 change

4h 9m • 1 change

4h 6m • 1 change

4h 10m • 1 change

4h 31m • 1 change

4h 9m • 1 change

4h 6m • 1 change
Want to know about travelling from Siena to Palestrina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Palestrina. However, there are services departing from Siena station and arriving at Palestrina station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 52m.
Siena to Palestrina bus services, operated by FlixBus, depart from Siena station.
Siena to Palestrina bus services, operated by FlixBus, arrive at PALESTRINA | Via Pio XII Via Pedemontana # f12260 station.
The distance between Siena and Palestrina is 208.4 km. The road distance is 272 km.
You can take a bus from Siena to PALESTRINA | Via Pio XII Via Pedemontana # f12260 via Roma, Autostazione Tiburtina, Ponte Mammolo, and ROMA | Ponte Mammolo in around 4h 31m.