The average bus between Siena and Domus Trevi, Rome takes 3h 52m and the fastest bus takes 3h 9m. The bus service runs several times per day from Siena to Domus Trevi, Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Siena and Domus Trevi, Rome. The earliest departure is at 5:35 AM in the morning, and the last departure from Siena is at 10:25 PM which arrives into Domus Trevi, Rome at 5:37 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 3h 52m. The schedules shown below are for the next available departures.

3h 40m • 1 change

3h 23m • 1 change

3h 32m • 1 change

3h 23m • 1 change

3h 45m • 1 change

3h 40m • 1 change

3h 23m • 1 change

3h 32m • 1 change

3h 45m • 1 change

3h 40m • 1 change

3h 23m • 1 change

3h 32m • 1 change

3h 45m • 1 change

3h 40m • 1 change

3h 23m • 1 change

3h 32m • 1 change

3h 45m • 1 change

3h 40m • 1 change

3h 23m • 1 change

3h 32m • 1 change

3h 35m • 1 change

3h 40m • 1 change

3h 13m • 1 change

3h 30m • 1 change
Want to know about travelling from Siena to Domus Trevi, Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Domus Trevi, Rome. However, there are services departing from Siena station and arriving at Domus Trevi, Rome station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 3h 52m.
Siena to Domus Trevi, Rome bus services, operated by FlixBus, depart from Siena station.
Siena to Domus Trevi, Rome bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Siena and Domus Trevi, Rome is 183.7 km. The road distance is 235 km.
FlixBus operates a bus from Siena to Roma, Autostazione Tiburtina every 3 hours. Tickets cost €16–28 and the journey takes 2h 50m. AutoLinee Moretti also services this route 3 times a week.