The average bus between Siena and Colosseum takes 4h 2m and the fastest bus takes 3h 16m. The bus service runs several times per day from Siena to Colosseum. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Siena and Colosseum. The earliest departure is at 3:00 PM in the afternoon, and the last departure from Siena is at 10:25 PM which arrives into Colosseum at 1:42 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 4h 2m. The schedules shown below are for the next available departures.
Arrives next day

3h 16m • 1 change
Arrives next day

3h 17m • 1 change
Arrives next day

4h 31m • 1 change
Arrives next day

3h 17m • 1 change
Want to know about travelling from Siena to Colosseum? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Colosseum. However, there are services departing from Siena station and arriving at Colosseum station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 2m.
Siena to Colosseum bus services, operated by FlixBus, depart from Siena station.
Siena to Colosseum bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Siena and Colosseum is 185.1 km. The road distance is 236 km.
FlixBus operates a bus from Siena to Roma, Autostazione Tiburtina every 3 hours. Tickets cost €16–27 and the journey takes 2h 50m. AutoLinee Moretti also services this route 3 times a week.