The average bus between Siena and Cento takes 5h 6m and the fastest bus takes 3h 25m. The bus service runs several times per day from Siena to Cento. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Siena and Cento. The earliest departure is at 6:40 AM in the morning, and the last departure from Siena is at 6:40 PM which arrives into Cento at 7:00 AM. All services require a transfer at Bologna Centrale and take an average of 5h 6m. The schedules shown below are for the next available departures.

4h 15m • 1 change

4h 5m • 1 change
Arrives next day

12h 20m • 1 change

3h 35m • 1 change

3h 50m • 1 change

4h 5m • 1 change

3h 35m • 1 change

3h 25m • 1 change

3h 35m • 1 change

3h 50m • 1 change

4h 5m • 1 change

3h 25m • 1 change

3h 35m • 1 change

3h 50m • 1 change

4h 10m • 1 change

4h 25m • 1 change

3h 55m • 1 change

4h 25m • 1 change

4h • 1 change

3h 25m • 1 change

3h 35m • 1 change

3h 50m • 1 change

4h 5m • 1 change
Want to know about travelling from Siena to Cento? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Cento. However, there are services departing from Siena station and arriving at Cento station via Bologna Centrale. The journey, including transfers, takes approximately 5h 6m.
Siena to Cento bus services, operated by FlixBus, depart from Siena station.
Siena to Cento bus services, operated by FlixBus, arrive at Cento Autostazione station.
The distance between Siena and Cento is 157.1 km. The road distance is 201 km.
You can take a bus from Siena to Cento Autostazione via Bologna Centrale and Indipendenza Nord in around 3h 56m.