The average bus between Setauket and Southold takes 3h 21m and the fastest bus takes 2h 26m. There is a bus service every few hours from Setauket to Southold. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Setauket and Southold. The earliest departure is at 6:16 AM in the morning, and the last departure from Setauket is at 10:53 PM which arrives into Southold at 7:40 AM. All services require a transfer at Port Jefferson LIRR and take an average of 3h 21m. The schedules shown below are for the next available departures.


2h 28m • 2 changes


2h 36m • 2 changes


2h 36m • 2 changes


2h 36m • 2 changes


2h 28m • 2 changes


2h 36m • 2 changes


2h 36m • 2 changes


2h 36m • 2 changes


2h 28m • 2 changes


2h 36m • 2 changes


2h 36m • 2 changes


2h 36m • 2 changes
Want to know about travelling from Setauket to Southold? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Setauket to Southold. However, there are services departing from Setauket station and arriving at Southold station via Riverhead LIRR. The journey, including transfers, takes approximately 3h 21m.
Setauket to Southold bus services, operated by Suffolk County Transit, depart from Port Jefferson LIRR station.
Setauket to Southold bus services, operated by Suffolk County Transit, arrive at NYS 25/Youngs Ave station.
The distance between Setauket and Southold is 59.9 km. The road distance is 79 km.
You can take a bus from NYS 25A/The Hills Dr to NYS 25/Youngs Ave via Port Jefferson LIRR and Riverhead LIRR in around 3h 14m.