The average bus between Schenectady and Buffalo takes 6h 52m and the fastest bus takes 5h 55m. The bus service runs several times per day from Schenectady to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Schenectady and Buffalo. The earliest departure is at 11:05 AM in the morning, and the last departure from Schenectady is at 8:30 PM which arrives into Buffalo at 4:00 AM. All services require a transfer, and take on average 6h 52m. The schedules shown below are for the next available departures.

5h 55m • 1 change

7h 5m • 1 change
Arrives next day

7h 25m • 1 change

5h 55m • 1 change

7h 5m • 1 change
Arrives next day

7h 25m • 1 change

5h 55m • 1 change

7h 5m • 1 change
Arrives next day

7h 25m • 1 change
Arrives next day

7h 30m • 1 change

5h 55m • 1 change

7h 5m • 1 change
Arrives next day

7h 25m • 1 change
Want to know about travelling from Schenectady to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Schenectady to Buffalo. However, there are services departing from Schenectady station and arriving at Buffalo station via Syracuse. The journey, including transfers, takes approximately 6h 52m.
Schenectady to Buffalo bus services, operated by Flixbus USA, depart from Schenectady station.
Schenectady to Buffalo bus services, operated by Flixbus USA, arrive at Buffalo station.
Book your Schenectady to Buffalo bus tickets online with Flixbus USA, Trailways and Greyhound USA.
The distance between Schenectady and Buffalo is 402.6 km. The road distance is 467 km.
You can take a bus from Schenectady to Buffalo via Syracuse Bus Station in around 6h 42m.